Targeting Inflammaging Before Visible Aging Begins
Skin aging is not only a result of time.
Daily exposure to UV radiation, pollution, allergens, oxidative stress, and repeated barrier disruption can keep the skin under persistent low-grade inflammatory stress. Over time, these factors may accelerate collagen degradation, weaken skin recovery, and contribute to redness, sensitivity, dullness, loss of firmness, and wrinkles.
This connection between chronic inflammation and accelerated aging is increasingly recognized as inflammaging. To support next-generation anti-aging formulations, ImDerma introduces four targeted actives addressing inflammation, oxidative stress, cellular recovery, and long-term skin resilience.

Flora Tone-COS — Protect Collagen
A Spilanthol-rich botanical active that helps reduce inflammatory signaling and MMP-1-related collagen degradation, supporting skin against inflammation-driven aging.

X-EGCG — Defend Against Intracellular Oxidative Stress
Combining EGCG with Peptide-X cell-penetrating technology, X-EGCG enhances intracellular delivery to rapidly neutralize ROS while supporting anti-inflammatory care, redness relief, and skin hydration.

ExoReishi — Accelerate Skin Recovery
Fermentation-derived extracellular vesicles enhance cellular communication and support skin repair and regeneration, helping stressed skin recover more efficiently.

Verperle-COS — Strengthen Skin Resilience
A patented green caviar active that helps reduce allergy-related responses and soothe sensitive skin while supporting Type I procollagen production for long-term skin resilience.

Key Inflammaging Concerns Addressed
✔ Chronic Low-Grade Inflammation
✔ Oxidative Stress
✔ Collagen Degradation
✔ Slower Skin Recovery
✔ Redness & Sensitivity
✔ Dullness & Loss of Firmness
✔ Fine Lines & Wrinkles

Beyond Wrinkle Correction
Next-generation anti-aging care should go beyond treating visible wrinkles. By targeting inflammatory stress, oxidative damage, collagen degradation, and reduced repair capacity, formulations can help support healthier and more resilient skin before visible aging becomes established.
By integrating Flora Tone-COS, X-EGCG, ExoReishi, and Verperle-COS, ImDerma provides a multi-target inflammaging strategy for advanced anti-aging and skin resilience formulations.

📩 Contact us for efficacy data, technical dossiers, formulation guidance, and active samples.

Reference URL：
Imdermalab® Flora Tone-COS
Imdermalab® X-EGCG
Imdermalab® ExoReishi
Imdermalab® Verperle-COS