Imdermalab® X-EGCG

Description

The X-peptide, a patented design sequence, has been proven to assist small molecule chemicals, peptides, macromolecular proteins and nano particles into intracellular delivery via pinocytosis mechanism. Our delivery system offers cosmetics innovation and technology by using patented X-peptide with pinocytosis mechanism to carry EGCG (catechin). As the result from DCFDA/ keratinocyte experiment, Imdermalab® X-EGCG anti-oxidant capacity is 24 times greater than EGCG without delivery system.

Benefit

Antioxidant
Spot Whitening
Anti-inflammatory
Anti-photoaging
Anti-Allergy

Mechanism of action

nhibit β-hexosamindase release induced by anti-IgE without cytotoxicity.
Eliminate intracellular ROS less than 1 hour, 24 times faster than pure EGCG.
Reduce UVB induced imflammatory

Tests

Efficacy Tests

In-Vitro: Intracellular ROS scavenge capbility test
In-vivo anti-aging, skin soothing, and skin barrier tests

Safety Tests

Passed the OECD 439 Alternative Skin Irritation Test
Passed the OECD 442C Test: no skin sensitisation

Application

Anti-pollution products
Anti-aging products
A post-sun relief product
Skin brightening products

INCI Name

Epigallocatechin Epigallocatechin gallate(and) sh-Decapeptide-5 SP (PCPC INCI)

Specification

Solubility: Water soluble
Appearance: White to slight yellowish powder
pH: 4.5~6.5 @25°C
Storage conditions: 4℃ - 25℃, avoid sunlight exposure and with humidity control

Dosage

0.1%-5%

Compliance

Award

2020 COSMETIC VICTORIES top 3 finalist selected
Patent Pending

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