Imdermalab® X-EGCG

Imdermalab® X-EGCG

Description

The X-peptide, a patented design sequence, has been proven to assist small molecule chemicals, peptides, macromolecular proteins and nano particles into intracellular delivery via pinocytosis mechanism. Our delivery system offers cosmetics innovation and technology by using patented X-peptide with pinocytosis mechanism to carry EGCG (catechin). As the result from DCFDA/ keratinocyte experiment, Imdermalab® X-EGCG anti-oxidant capacity is 24 times greater than EGCG without delivery system.

Benefit

  • Antioxidant
  • Spot Whitening
  • Anti-inflammatory
  • Anti-photoaging
  • Anti-Allergy

Mechanism of action

  • nhibit β-hexosamindase release induced by anti-IgE without cytotoxicity.
  • Eliminate intracellular ROS less than 1 hour, 24 times faster than pure EGCG.
  • Reduce UVB induced imflammatory

Tests

Efficacy Tests

  • In-Vitro: Intracellular ROS scavenge capbility test
  • In-vivo anti-aging, skin soothing, and skin barrier tests

Safety Tests

  • Passed the OECD 439 Alternative Skin Irritation Test
  • Passed the OECD 442C Test: no skin sensitisation

Application

  • Anti-pollution products
  • Anti-aging products
  • A post-sun relief product
  • Skin brightening products

INCI Name

Epigallocatechin Epigallocatechin gallate(and) sh-Decapeptide-5 SP (PCPC INCI)

Specification

Solubility: Water soluble
Appearance: White to slight yellowish powder
pH: 4.5~6.5 @25°C
Storage conditions: 4℃ - 25℃, avoid sunlight exposure and with humidity control

Dosage

0.1%-5%

Compliance

Award

2020 COSMETIC VICTORIES top 3 finalist selected
Patent Pending

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